Self-Maintaining Electrode–Skin Interface for Motion-Robust Biosignal Monitoring

Tran Quang Trung, Shamanth Kuthpadi Seethakantha, Zhenyu Lei, Amirmohammad Radmehr, Phuc Nguyen, Deepak Ganesan
Advanced Healthcare Materials · 2026 ↗
Abstract

The electrode–skin interface presents a fundamental challenge in bioelectronics: maintaining stable electrical contact with tissue that undergoes constant physiological changes. Here we demonstrate a paradigm shift by engineering a self-sustaining microenvironment at the skin–electrode interface through the integration of Au-coated fabric electrodes with a humidity-regulating cooling patch. Our smart electrode-integrated cooling (SEIC) patch uses evaporative cooling to create a humid microenvironment where water condensation continuously regenerates ionic pathways between skin and electrode. This transforms the interface from a static contact point to a dynamic, self-renewing electrochemical junction. The SEIC patch exhibits 200-fold and 10-fold lower impedances than Au-coated fabric electrodes and conventional electrodes, respectively; maintains performance through 2000 attachment cycles; enables stable biosignal acquisition for eight days; and preserves signal fidelity under motion. Moreover, the SEIC demonstrates applications in continuous cardiac monitoring during daily life, and real-time 3D facial animation reconstruction in virtual reality via high-fidelity capture of facial muscle activity. This work opens new frontiers in preventive medicine and human–computer interaction.

Read the paper ↗

VYRE: Low-Burden and Robust Oscillometric Ring-Based System for Frequent Blood Pressure Monitoring

Amirmohammad Radmehr, Shamanth Kuthpadi Seethakantha, Abdul Aziz, Quang Trung Tran, Aryan Nair, William Saulnier, Deepak Ganesan, Phuc Nguyen
SenSys '26 · 2026 ↗
Abstract

In this paper, we present VYRE, a ring-based oscillometric wearable designed for low-burden and robust frequent blood pressure monitoring. VYRE revisits the clinically established oscillometric method — widely accepted in arm and wrist form factors because of its high accuracy — and extends it to a compact ring form factor, currently realized as a proof-of-concept prototype. The key innovation is the ability to derive oscillometric signals on the finger by inducing controlled inflation and deflation to capture arterial oscillations in response to circumferential tension. This enables accurate estimation of blood flow dynamics within the digital arteries for blood pressure inference. VYRE leverages a lightweight model to estimate systolic and diastolic pressures from the measured oscillations observed from a vibration sensor integrated into the ring. Compared to PPG-based methods, this approach offers significant improvement in robustness to signal drift, ambient light variations, and skin tone differences. Each measurement requires a user-initiated ∼ 40-second quiet hold, after which the system returns systolic and diastolic readings without per-user calibration. In an IRB-approved study involving 71 participants, VYRE achieves mean absolute errors of 6.36 mmHg for systolic and 4.96 mmHg for diastolic pressure relative to a reference cuff, with biases of − 1.27mmHg and 0.0mmHg, respectively. The standard deviations of 7.87 mmHg (SBP) and 6.22 mmHg (DBP) meet the AAMI requirements (≤ 8mmHg), and 95% limits of agreement fall within [ − 16.69, 14.15] mmHg for systolic and [ − 12.2, 12.19] mmHg for diastolic pressure. Correlation with the reference is strong (Pearson r = 0.75 for SBP, r = 0.67 for DBP), confirming consistent tracking. The system maintained accuracy across finger sizes and hand postures. User feedback indicated that 84% of participants rated the device as comfortable or very comfortable, and 70% expressed willingness to use it daily. These results confirm VYRE’s practicality, accuracy, and potential as a compact, on-demand blood pressure monitoring solution.

Read the paper ↗

IOTeeth: Intra-Oral Teeth Sensing System for Dental Occlusal Diseases Recognition

Zhizhang Hu*, Amirmohammad Radmehr*, Yue Zhang, Shijia Pan, Phuc Nguyen
Proc. ACM Interact. Mob. Wearable Ubiquitous Technol. · 2024 ↗
Abstract

While occlusal diseases - the main cause of tooth loss -- significantly impact patients' teeth and well-being, they are the most underdiagnosed dental diseases nowadays. Experiencing occlusal diseases could result in difficulties in eating, speaking, and chronicle headaches, ultimately impacting patients' quality of life. Although attempts have been made to develop sensing systems for teeth activity monitoring, solutions that support sufficient sensing resolution for occlusal monitoring are missing. To fill that gap, this paper presents IOTeeth, a cost-effective and automated intra-oral sensing system for continuous and fine-grained monitoring of occlusal diseases. The IOTeeth system includes an intra-oral piezoelectric-based sensing array integrated into a dental retainer platform to support reliable occlusal disease recognition. IOTeeth focuses on biting and grinding activities from the canines and front teeth, which contain essential information of occlusion. IOTeeth's intra-oral wearable collects signals from the sensors and fetches them into a lightweight and robust deep learning model called Physioaware Attention Network (PAN Net) for occlusal disease recognition. We evaluate IOTeeth with 12 articulator teeth models from dental clinic patients. Evaluation results show an F1 score of 0.97 for activity recognition with leave-one-out validation and an average F1 score of 0.92 for dental disease recognition for different activities with leave-one-out validation.

Read the paper ↗

Hardware-Assisted Privacy-Preserving Multi-Channel EEG Computational Headwear

Bhawana Chhaglani, Abdul Aziz, Amirmohammad Radmehr, Joseph Collins, Jeremy Gummeson, Sunghoon Ivan Lee, Ravi Karkar, Phuc Nguyen
2024 IEEE 20th International Conference on Body Sensor Networks (BSN) · 2024
Abstract

EEG signals contain highly sensitive information about an individual's mental state, cognitive processes, and health conditions, making privacy preservation crucial. With the rise of commercial headwear capable of capturing EEG signals, developing robust mechanisms for ensuring privacy of such data is imperative. This work aims to protect EEG data privacy in cloud-based processing systems by sending intermediate output after neural network layer splitting to the cloud. We propose a novel holistic Combined Privacy Metric (CPM) that quantifies privacy leakage between raw EEG signals and intermediate outputs. Our study focuses on EEG-based seizure detection using a 1D CNN architecture, achieving accuracy of 96.25%. We evaluate various splitting configurations to optimize the trade-off between privacy preservation and computational efficiency. We find that splitting after the second convolutional layer achieves a CPM of 0.82 with a modest client-side model size of 509kB. This approach significantly enhances EEG data privacy while enabling effective cloud-based analysis, potentially facilitating wider adoption of secure EEG technologies in healthcare and research applications.

A Platform-Agnostic Physiological Signal Compression Approach for Resource-Constrained Computational Headwear

Neel Vora*, Amir Hajighasemi*, Cody T. Reynolds, Amirmohammad Radmehr, Mohamed Mohamed, Saurav Rahman, Abdul Aziz, Jai Veerla, Mohammad Nasr, Hayden Lotspeich, Partha Guttikonda, Thuong Pham, Aarti Darji, Parisa Boodaghi, Helen Shang, Jay Harvey, Kan Ding, VP Nguyen, Jacob Luber
2024 IEEE 20th International Conference on Body Sensor Networks (BSN) · 2024
Abstract

Head-based signals such as EEG, EMG, EOG, and ECG collected by wearable systems play a pivotal role in clinical diagnosis, monitoring, and treatment of important brain disorder diseases. However, head-based signal processing systems often produce complex signals, making wearable inference for diagnosis impractical, especially when the signals are weak. This is common with head-worn sensors due to poor contact. Moreover, the real-time transmission of a large corpus of physiological signals over extended periods consumes significant power and time, limiting the viability of battery-dependent physiological monitoring headwear. To address these issues, this paper presents a deep-learning framework employing a variational autoencoder (VAE) for physiological signal compression to reduce wearables' computational complexity and energy consumption. Our approach achieves an impressive compression ratio of 1:585 specifically for spectrogram data, surpassing state-of-the-art compression techniques such as JPEG2000, H.264, Direct Cosine Transform (DCT), and Huffman Encoding, which do not excel in handling physiological signals. We validate the efficacy of the compressed algorithms using collected physiological signals from real patients in the clinic and deploy the solution on a commonly used embedded AI chip for headwear systems (i.e., ARM Cortex). The proposed framework achieves a 91% seizure detection accuracy, confirming the approach's reliability, practicality, and scalability.

Experimental Study on the Imitation of the Human Head-and-Eye Pose Using the 3-DOF Agile Eye Parallel Robot with ROS and Mediapipe Framework

Amirmohammad Radmehr, Milad Asgari, Mehdi Tale Masouleh
2021 9th RSI International Conference on Robotics and Mechatronics (ICRoM) · 2021 ↗
Abstract

In this paper, a method to mimic a human face and eyes is proposed which can be regarded as a combination of computer vision techniques and neural network concepts. From a mechanical standpoint, a 3-DOF spherical parallel robot is used which imitates the human head movement. In what concerns eye movement, a 2-DOF mechanism is attached to the end-effector of the 3-DOF spherical parallel mechanism. In order to have robust and reliable results for the imitation, meaningful information should be extracted from the face mesh for obtaining the pose of a face, i.e., the roll, yaw, and pitch angles. To this end, two methods are proposed where each of them has its own pros and cons. The first method consists in resorting to the so-called Mediapipe library which is a machine learning solution for high-fidelity body pose tracking, introduced by Google. As the second method, a model is trained by a linear regression model for a gathered dataset of face pictures in different poses. In addition, a 3-DOF Agile Eye parallel robot is utilized to show the ability of this robot to be used as a system which is similar to a human head for performing a 3-DOF rotational motion pattern. Furthermore, a 3D printed face and a 2-DOF eye mechanism are fabricated to display the whole system more stylish way. Experimental tests, which are done based on a ROS platform, demonstrate the effectiveness of the proposed methods for tracking the human head and eye movement.

Read the paper ↗